PRAESIIDIUM: Mathematical Models and Artificial Intelligence for the Prevention of 2 Diabetes

For the achievement of the Horizon Europe project results, PRAESIIDIUM, numerous research groups are combining their expertise to develop innovative strategies for the prevention of type 2 diabetes, integrating mathematical models, biological simulations, and reliable, explainable artificial intelligence tools.

The special feature of this issue is once again dedicated to the stories of three experts involved in the European project PRAESIIDIUM: Alessia Paglialonga, Laura Azzimonti, and Paolo Tieri.

Special Issue 3 is dedicated to presenting — and discussing — reliable, interpretable, and generalizable models, which are essential in the medical field.

PRAESIIDIUM Special 3- ENG

Why is prevention, even before prediabetes appears, important?

36% of European adults live with undiagnosed diabetes, which can cause potentially life-threatening complications if not treated promptly and adequately.

541 million adults have “blood glucose levels higher than normal but not high enough to be classified as diabetes” (IDF Diabetes Atlas, 10th edition).

“Impaired fasting glucose” is an intermediate condition also known as prediabetes, as it can precede the onset of type 2 diabetes.

The most important point is that prediabetes is reversible if diagnosed early and properly, through lifestyle interventions such as a healthy diet and regular physical activity (WHO 2014 and IDF recommendations).

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